Defense = American Standard English
Defence = Standard English
The pronunciation is also different.
In Britain, it's 'de-fence,' with a little more stress on the second syllable, while in America it's 'DE-fence,' with much stress on the first syllable. We do say 'Defensive' rather than 'Defencive' though, so we're just inconsistent in our grammar rules. You can thank Webster for making American Standard English have more consistent rules of grammar (I still like Standard English better though
)
There's also the matter of 'Offence' and 'Offense,' which have the same differences in Britain and America as Defense/Defence.
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Isn't this stupid? Its like saying cat or kat, cow or kow. Why can't you people at least talk in the same "english"?